Why we ran this comparison
RxPros gets several things right. Plans start at $99.99 a month, paid annually, and every dose costs the same, so the price holds as your dose goes up. You can pick compounded semaglutide or tirzepatide, each with vitamins mixed in. It also has a 4.7 on Trustpilot from 24,948 reviews, far more than Hume Care's 2,918.
RxPros's refund agreement sets a three-month minimum, since three months of medication ship upfront, and canceling early costs a fee equal to the full retail monthly price for the rest of the commitment. Its homepage line "Cancel Subscription Anytime" reads differently from those terms. Hume Care lets you cancel anytime up to 48 hours before renewal, tracks fat and muscle with a weekly scan, and backs the plan with a 90-day results guarantee (eligibility and adherence conditions apply).
We compared them on what you'd want settled before handing over a card: the monthly price, how long you're tied in, what gets tracked, how you reach a clinician, what's guaranteed and what happens when you stop. Here's what we found.
At a glance: Hume Care vs. RxPros
The two options side by side, before the detail.
| Spec | Hume Care | RxPros |
|---|---|---|
| What you get | Medication with glycine, B12 and B6, a free Body Pod, the app and clinicians | Medication with added vitamins, a doctor visit and overnight shipping |
| Commitment | Cancel anytime, 48 hours before renewal | 3-month minimum; fee to cancel early |
| Body-composition tracking | Weekly body scan on a free Body Pod ($352 value) | None on RxPros's site |
| Results guarantee | 90-day results guarantee (conditions apply) | None; full refund if not prescribed |
| App | Hume app for doses, food logging and messages | Web patient portal for messages |
| Pricing | Introductory offer from $199/month | From $99.99/mo (semaglutide) or $144.97/mo (tirzepatide), paid annually |
| Medication choice | Chosen by your provider | Compounded semaglutide or tirzepatide |
| Clinician access | USA clinician on your team, plus video visits | Online consult; portal messages and scheduled visits by plan |
| Reviews | 4.7 on Trustpilot (2,918 reviews) | 4.7 on Trustpilot (24,948 reviews) |
Green marks the stronger option in each row. RxPros takes three of the nine.
Reason 1: Hume Care Shows You Whether You're Losing Fat or Muscle
A drop on the bathroom scale can be fat, muscle or both, and the number by itself won't say which. We looked at what each program gives you for seeing the split at home.
A free Hume Body Pod smart scale ($352 value) comes with every HumeCare+ membership. Once a week you step on it for a body scan that reads body fat, muscle mass, visceral fat and 45+ body-composition metrics, so you can watch fat and muscle change separately.
- A weekly body scan at home that reports body fat and muscle mass separately
- Visceral fat plus 45+ body-composition metrics, tracked alongside your weight
- If your muscle mass dips, next week's scan shows it, and you can message your care team
- RxPros's site lists no tool or scale for tracking body composition
- Your RxPros clinician may ask you to share your current weight
- Its help center says clinicians may also ask for blood pressure or lab tests
If I'm losing weight on a weekly shot, I want to know how much of it is fat and how much is muscle. Hume Care's free Body Pod shows me that split with a weekly scan. I'd step on it every week and message my care team when a number looked off.
Reason 2: Both Add Vitamins. Hume Care Adds a Nutrition Plan, Too
Both programs include glycine, B12 and B6, so we're calling the vitamins a tie. Then we looked at what each one offers for food and dosing.
- You get nutrition and hydration guidance as part of the HumeCare+ protocol
- A daily food log in the Hume app tracks calories and macros
- Your care team adjusts your dose as you go, and side-effect support is there anytime
- Its homepage lists B6, B12 and glycine added to the compound
- Every dose costs the same flat monthly price, from $99.99 on an annual plan
- We found no nutrition program or food log anywhere on the RxPros site
The food side is what would sway me here. Logging my meals in the same app where I track my doses, and watching calories and macros add up, would keep me honest. RxPros's flat price across every dose is a fair plus for anyone moving up in dose.
Reason 3: Your Doses, Your Food Log and Your Care Team Live in One App
A weekly shot brings weekly questions. Hume Care handles them in its phone app, and RxPros uses a web patient portal.
- Your care team includes a USA clinician, and you can meet by video
- Your care team sets a personalized dose and keeps adjusting it
- Log shots and meals, see calories and macros, and message your team without leaving the app
- Doctor and support messages go through a web patient portal
- Check-ins come by portal questionnaire, message or scheduled visit, depending on your plan
- We couldn't find a phone app on its site; the portal runs in a web browser
I'd be logging meals and shots most days, so I'd pick the Hume app, which keeps that log and my care team in one place. For messages alone, RxPros's portal does the job.
Reason 4: No Minimum Term, Plus a Results Guarantee
Here's what each program costs, how long it holds you and what it promises.
- A 90-day results guarantee in writing; eligibility and adherence conditions apply
- A limited-time introductory offer from $199/month, HSA/FSA accepted
- Automatic refills you can cancel anytime up to 48 hours before renewal
- A 3-month minimum, because three months of medication ship upfront
- Cancel early and the fee equals the remaining months at the full retail monthly price
- No refunds after the medical consult, unless the doctor declines to prescribe
If you want the lowest monthly price and you're ready to commit for at least three months, RxPros makes sense. I'd pay Hume Care's higher price for the freedom to cancel in any month and a 90-day results guarantee (conditions apply).
Reason 5: Side-Effect Support Anytime, Plus Video Visits With Your Clinician
Say a side effect shows up on a Sunday night. Both programs give you a clinician you can message from your couch.
- Side-effect support anytime you need it, as part of the membership
- Video visits to talk things over with your clinician
- Messages to your care team go through the Hume app on your phone
- An online consult with a licensed provider, and approval within 24 hours
- RxPros says its team is "just a text away" through the patient portal
- Zofran for nausea is an add-on after checkout, which we count in its favor
I'd want side-effect support at any hour and video visits with my clinician, and Hume Care builds both into the membership. If nausea worries you, RxPros's Zofran add-on is worth asking about too.
Reason 6: Hume Care Has a Plan for the Day You Stop the Shots
Stopping the shots has a known downside. A year after people in the STEP 1 trial extension came off the GLP-1 medication tested, they had put two-thirds of the lost weight back on. Ask any program what it does about that.
- Post-medication guidance, so you have a plan for the months after your last dose
- Nutrition guidance and food logging habits you build during treatment
- Glycine, B12 and B6 to help protect muscle, and body scans to see what you keep
- We found no program on RxPros's site for the months after you stop taking the medication
- Its own fine print says featured users exercised daily and ate fewer calories
- Its help center offers general articles on eating and exercise while on GLP-1s
Habits decide what happens after the last dose, and I'd want mine in place before I got there. Hume Care has you logging meals and following nutrition guidance throughout, then gives you post-medication guidance when the shots stop. That's why it's our pick.
Feature-by-feature comparison
Every row that matters, side by side. RxPros gets credit where it earns it.
| Feature | Hume Care | RxPros |
|---|---|---|
| Body-composition tracking at home | ✓ | ✗ (none listed) |
| Results guarantee | ✓ (90-day, conditions apply) | ✗ (refund only if declined) |
| Cancel without a minimum term | ✓ (cancel anytime) | ✗ (full refund if declined) |
| Phone app for doses and food logging | ✓ | ✗ (web portal) |
| Glycine, B12 and B6 included | ✓ | ✓ (in the compound) |
| Choice of medication | ✗ (provider decides) | ✓ (semaglutide or tirzepatide) |
| Lower monthly price | ✗ (from $199/mo intro) | ✓ (from $99.99/mo, annual) |
| Larger review base | ✗ (2,918 reviews) | ✓ (24,948 reviews) |
| Post-medication guidance | ✓ (built in) | ✗ (none listed) |
| Total checks | 6/9 | 4/9 |
Hume Care Wins for Most People
We read both companies' pages closely, terms and all, and Hume Care is the program we'd point most people to. RxPros earns real credit here. Its monthly price is lower, and flat across doses. You can choose between two compounded GLP-1 medications. Its homepage lists glycine, B12 and B6 in the shots, the same three Hume Care builds into its protocol. And it has 24,948 reviews on Trustpilot, a much bigger base than Hume Care's 2,918.
Hume Care leads on terms and on what you get each week. RxPros ships three months of medication upfront, sets a three-month minimum, and gives no refund after the consult unless the doctor declines to prescribe. Hume Care lets you cancel anytime and backs the plan with a 90-day results guarantee (eligibility and adherence conditions apply). On top of that come weekly body scans on a free Body Pod, nutrition guidance and a food log in the Hume app, video visits with your clinician, and guidance for after your last dose.
Pick RxPros if the lowest monthly price for a compounded shot matters most to you, you already know which medication you want, and a three-month commitment at the start suits you. Everyone else should start with Hume Care. You can leave whenever you like, the weekly scan tells you whether the weight coming off is fat or muscle, and the care team keeps tuning your dose along the way.
A physician-guided peptide protocol with glycine, B12 and B6, weekly body scans on a free Hume Body Pod ($352 value), a clinician team in the app and a 90-day results guarantee (conditions apply). Intro offer from $199/month.
Start Your Assessment →What HumeCare+ Members Are Saying
Stories from HumeCare+ members, edited for length and clarity. Individual results vary.
"I'd done GLP-1 before, and the weight came straight back the moment I stopped. This time I had support the whole way through, and I've kept it off since finishing the protocol. I've got a lot more energy, too."
"Diets never worked for me, and my first try at GLP-1 medication made me so sick I was scared to go near it again. I'm glad I gave it one more shot. I had zero side effects the whole way through on my clinician's protocol."
"I can't really put the confidence into words. The fears and insecurities are behind me, I've stopped worrying over every little ache, and I feel ready for this new way of living."